With therapeutic doses of TCAs, barbiturates improve metabolism and decrease blood concentrations of TCAs.

Check Intently (1)pentobarbital will lower the level or outcome of levamlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

Minimal (1)pentobarbital will lessen the extent or impact of paclitaxel protein sure by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.

Contraindicated (1)pentobarbital will reduce the level or result of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with solid CYP3A4 inducers will not be advisable

With therapeutic doses of TCAs, barbiturates increase metabolism and decrease blood concentrations of TCAs.

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fentanyl transdermal and pentobarbital both improve sedation. Stay away from or Use Alternate Drug. Limit use to clients for whom option cure alternatives are inadequate

pentobarbital will reduce the level or outcome of fludrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

pentobarbital will decrease the level or result of repaglinide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

Observe Intently (1)pentobarbital will lower the level or outcome of linagliptin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Use of other treatment options is strongly recommended when linagliptin is to be administered that has a CYP3A4 inducer

pentobarbital will minimize the level or here result of zaleplon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unidentified.

pentobarbital will lessen the level or impact of fosamprenavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

pentobarbital will reduce the level or influence of voriconazole by impacting hepatic enzyme CYP2C9/ten metabolism. Minor/Importance Not known.

pentobarbital will decrease the extent or effect of ritonavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.